The assay revealed a remarkable decrease in the association of TCF-4 to the Tcf-responsive sites in the promoters of Wnt-signalling target genes (Figure 7).
In this report we reveal that the evolutionary conserved Dazap2 protein functions as a TCF-4 interacting partner. We demonstrate that a short region proximal to ...
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A major outcome of the canonical Wnt/beta-catenin-signalling pathway is the transcriptional activation of a specific set of target genes.
In this report we reveal that the evolutionary conserved Dazap2 protein functions as a TCF-4 interacting partner. We demonstrate that a short ...
T-cell factor 4 (TCF4), together with β-catenin coactivator, functions as the major transcriptional mediator of the canonical wingless/integrated (Wnt) ...
Wnt Effector TCF4 Is Dispensable for Wnt Signaling in Human Cancer Cells ... Dazap2 modulates transcription driven by the Wnt effector TCF-4.
The knockdown of DAZAP2 does not only lessen the activity of Wnt signaling as measured by Tcf/-catenin reporters, but it also changes the expression of Wnt ...
Dazap2 modulates transcription driven by the Wnt effector TCF-4. Nucleic Acids Res 37, 3007–3020. doi:10.1093/nar/gkp179. OpenUrlCrossRef ...
Dazap2 modulates transcription driven by the Wnt effector TCF-4. Lukas J ... methylation of DAZAP2 promoter was involved in downregulation of DAZAP2 in ...
Enhances the binding of transcription factor TCF7L2/TCF4, a Wnt signaling pathway effector, to the promoters of target genes (By similarity). Plays a role in ...