This review explores the emerging role of amino acid metabolism in ASCVD, uncovering novel potential biomarkers, causative factors, and therapeutic targets.
Typically, AAs serve as basic components for protein synthesis usually as metabolites or intermediates in cellular pathways where they ...
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In this review, we focus on the interplay between amino acids, especially L-leucine, L-arginine, and L-glutamine, and autophagy during atherosclerosis ...
It has emerged that a strong relationship exists between alterations in amino acid (AA) metabolism and the development of atherosclerosis.
These amino acids and their metabolites have been implicated in various processes characteristic of ASCVD including impaired lipid metabolism, endothelial ...
This MR study demonstrated significant causal effects of circulating levels of AAs on CVDs, indicating the potential use of AAs as biomarkers or ...
Myocardial metabolic alterations in mice with diet-induced atherosclerosis: linking sulfur amino acid and lipid metabolism. Jueun Lee ...
Despite significant advances in medical treatments and drug development, atherosclerotic cardiovascular disease (ASCVD) remains a leading cause of death ...
Elevated BCAA levels are associated with atherosclerosis development, and tryptophan and its metabolites have complex effects on CHD. Notably, ...
The development and progression of atherosclerosis, which ultimately gives rise to cardiovascular disease, has been causally linked to.